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Journal article

Inhibitory effect of TIMP influences the morphology of varicose veins.

Abstract:

OBJECTIVES: Imbalance of matrix metalloproteinase enzymes (MMP) and their inhibitors (TIMPs) may contribute to the development of varicose veins. We hypothesised that, histological changes in varicose vein wall correlate with alterations in expression of MMP/TIMP. METHODS: Varicose veins (n=26) were compared with great saphenous vein (GSV) segments (n=11) from arterial bypass, and with arm and neck veins from fistula and carotid operations (n=13). Varicose vein wall thickness was measured, e...

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Publication status:
Published

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Publisher copy:
10.1016/j.ejvs.2010.04.028

Authors


Aravind, B More by this author
Saunders, B More by this author
Sandison, A More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS, BHF Centre of Research Excellence
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Journal:
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
Volume:
40
Issue:
6
Pages:
754-765
Publication date:
2010-12-05
DOI:
EISSN:
1532-2165
ISSN:
1078-5884
URN:
uuid:8255f559-8ccd-4b01-867e-aad3186f6257
Source identifiers:
226766
Local pid:
pubs:226766

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