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Journal article

Engineered method for directional growth of muscle sheets on electrospun fibers

Abstract:

Research on the neuromuscular junction (NMJ) and its function and development spans over a century. However, researchers are limited in their ability to conduct experimentation on this highly specialized synapse between motor neurons and muscle fibers, as NMJs are not easily accessible outside the body. The aim of this work is to provide a reliable and reproducible muscle sheet model for in vitro NMJ study. A novel culture system was designed by engineering a method for the directional growth...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1002/jbm.a.36312

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Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; Weatherall Insti. of Molecular Medicine
Role:
Author
ORCID:
0000-0002-3782-9045
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
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China Regenerative Medicine International More from this funder
Clarendon Fund More from this funder
Publisher:
Wiley Publisher's website
Journal:
Journal of Biomedical Materials Research Part A Journal website
Volume:
106
Issue:
5
Pages:
1165-1176
Publication date:
2018-01-09
Acceptance date:
2017-12-15
DOI:
EISSN:
1552-4965
ISSN:
1549-3296
Pubs id:
pubs:812798
URN:
uri:824a055e-e823-4260-8308-e59edcb138b9
UUID:
uuid:824a055e-e823-4260-8308-e59edcb138b9
Local pid:
pubs:812798

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