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Uptake of 99mTc-exametazime shown by single photon emission computed tomography before and after lithium withdrawal in bipolar patients: associations with mania.

Abstract:

BACKGROUND: Early manic relapse following lithium discontinuation offers an important opportunity to investigate the relationship between symptoms, effects of treatment and regional brain activation in bipolar affective disorder. METHOD: Fourteen stable bipolar patients on lithium were examined with neuropsychological measures, clinical ratings and single photon emission computed tomography (SPECT) before and after acute double-blind withdrawal of lithium. Brain perfusion maps were spatially ...

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Publisher copy:
10.1192/bjp.170.5.426

Authors


Goodwin, GM More by this author
Cavanagh, JT More by this author
Glabus, MF More by this author
O'Carroll, RE More by this author
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Journal:
The British journal of psychiatry : the journal of mental science
Volume:
170
Issue:
5
Pages:
426-430
Publication date:
1997-05-05
DOI:
EISSN:
1472-1465
ISSN:
0007-1250
URN:
uuid:8248cfc5-cacc-42cf-b4a8-66e06f0d9c24
Source identifiers:
139307
Local pid:
pubs:139307

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