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Journal article

Mannose receptor interacts with Fc receptors and is critical for the development of crescentic glomerulonephritis in mice.

Abstract:

Crescentic glomerulonephritis (CGN), which frequently results in acute and chronic kidney disease, is characterized by and dependent on glomerular infiltration by macrophages. The mannose receptor (MR) is a pattern recognition receptor implicated in the uptake of endogenous and microbial ligands by macrophages, mesangial cells (MCs), and selected endothelial cells. It is upregulated on alternatively activated macrophages (i.e., macrophages associated with tissue repair and humoral immunity) a...

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Publication status:
Published

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Publisher copy:
10.1172/jci41560

Authors


Chavele, KM More by this author
Martinez-Pomares, L More by this author
Pemberton, S More by this author
Haslam, SM More by this author
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Journal:
The Journal of clinical investigation
Volume:
120
Issue:
5
Pages:
1469-1478
Publication date:
2010-05-05
DOI:
EISSN:
1558-8238
ISSN:
0021-9738
URN:
uuid:8235d201-5de1-4b44-ab76-bf38095e03dc
Source identifiers:
54819
Local pid:
pubs:54819

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