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The high rate of familial lichen sclerosus suggests a genetic contribution: an observational cohort study.

Abstract:

BACKGROUND: Familial lichen sclerosus (LS) has been described in only 37 families. We feel that the association is under-reported. OBJECTIVES: To determine the percentage of patients with LS who have a positive family history. METHOD: A large observational-cohort study of a total of 1052 females at vulval clinics within a University Hospital with a diagnosis of LS of the vulva (clinical diagnosis was confirmed in 80% of cases by histology). Patients were questioned as to family history of LS...

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Publication status:
Published

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Authors


Sherman, V More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Medicine Division
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Journal:
Journal of the European Academy of Dermatology and Venereology : JEADV
Volume:
24
Issue:
9
Pages:
1031-1034
Publication date:
2010-09-05
DOI:
EISSN:
1468-3083
ISSN:
0926-9959
URN:
uuid:822b9b42-025c-40b8-b615-f7005ffd0ab0
Source identifiers:
50302
Local pid:
pubs:50302

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