Thesis
Molecular biology of X-chromosome disease
- Abstract:
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Genomic clones were isolated and characterized using the human monoamine oxidase A (MAOA) cDNA to screen a phage library, constructed from a human 4X cell line (48, XXXX). The genomic contig derived from overlapping phage clones showed that the size of the MAOA gene is over 80 kb. Exon-containing fragments from these phage clones were subcloned and sequenced. The data from this showed that the MAOA gene consists of 15 exons.
A YAC (yeast artificial chromosome) isolated using the MA...
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Bibliographic Details
- Publication date:
- 1992
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Source identifiers:
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603849131
Item Description
- Language:
- English
- Subjects:
- UUID:
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uuid:8214a2f6-0bfa-4ea4-8f48-b8a20f29318c
- Local pid:
- td:603849131
- Deposit date:
- 2013-06-22
Terms of use
- Copyright holder:
- Chen, Zheng-Yi
- Copyright date:
- 1992
- Notes:
- The digital copy of this thesis has been made available thanks to the generosity of Dr Leonard Polonsky
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