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Thesis

Molecular biology of X-chromosome disease

Abstract:

Genomic clones were isolated and characterized using the human monoamine oxidase A (MAOA) cDNA to screen a phage library, constructed from a human 4X cell line (48, XXXX). The genomic contig derived from overlapping phage clones showed that the size of the MAOA gene is over 80 kb. Exon-containing fragments from these phage clones were subcloned and sequenced. The data from this showed that the MAOA gene consists of 15 exons.

A YAC (yeast artificial chromosome) isolated using the MA...

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Institution:
University of Oxford
Department:
Life and Environmental Sciences Division
Role:
Author

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Role:
Supervisor
Publication date:
1992
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Barcode:
603849131
URN:
uuid:8214a2f6-0bfa-4ea4-8f48-b8a20f29318c
Local pid:
td:603849131

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