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The molecular basis of metabolic cycles and their relationship to circadian rhythms

Abstract:

Metabolic cycles result from the partitioning of oxidative and reductive metabolism into rhythmic phases of gene expression and oscillating post-translational modifications to proteins. Relatively little is understood about how the switches in gene expression are controlled during a metabolic cycle, although recent studies have suggested a central role for transcription itself, via extensive transcriptional interference involving non-coding transcription, in rhythmically switching genes on an...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1038/nsmb.3311

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Department:
Oxford, MSD, Biochemistry
Publisher:
Nature Publishing Group Publisher's website
Journal:
Nature Structural and Molecular Biology Journal website
Volume:
23
Issue:
12
Pages:
1035–1044
Publication date:
2016-12-06
Acceptance date:
2016-09-23
DOI:
EISSN:
1545-9985
ISSN:
1545-9993
Pubs id:
pubs:646368
URN:
uri:81f5ed2d-d2d1-476b-8407-9bcdd9ab21a3
UUID:
uuid:81f5ed2d-d2d1-476b-8407-9bcdd9ab21a3
Local pid:
pubs:646368

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