- Abstract:
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Policy Points:
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- For complex reasons, the promise of “precision medicine” based on molecular pathways remains unrealized for many conditions.
- Clinical practice guidelines (theoretically, at least) can act as “trailblazers” to introduce tests and treatments that reflect precision medicine discoveries.
- We describe a detailed case study from the United Kingdom in which such an attempt was (so far) unsuccessful and show how this case provides generalizabl... - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Files:
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(, 0.0b)
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- Publisher copy:
- https://doi.org/10.1111/1468-0009.12455
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- Publisher:
- Wiley Publisher's website
- Journal:
- Milbank Quarterly Journal website
- Volume:
- 98
- Issue:
- 2
- Pages:
- 581-617
- Publication date:
- 2020-05-20
- Acceptance date:
- 2019-11-22
- DOI:
- EISSN:
-
1468-0009
- ISSN:
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0887-378X
- Pubs id:
-
pubs:1080846
- UUID:
-
uuid:81e962f4-cc37-4ebb-94e1-618ed5acf4ae
- Source identifiers:
-
1080846
- Local pid:
- pubs:1080846
- Language:
- English
- Keywords:
- Copyright holder:
- Rushforth and Greenhalgh
- Rights statement:
- © 2020 The Authors. The Milbank Quarterly published by Wiley Periodicals, Inc. on behalf of The Millbank Memorial Fund This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- License:
- CC Attribution (CC BY)
Journal article
Personalised medicine, disruptive innovation and ‘trailblazer’ guidelines: Case study and theorization of an unsuccessful change effort
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