- Abstract:
-
Metastasis via the lymphatics is a major risk factor in squamous cell carcinoma of the oral cavity (OSCC). We sought to determine whether the presence of metastasis in the regional lymph node could be predicted by a gene expression signature of the primary tumor. A total of 18 OSCCs were characterized for gene expression by hybridizing RNA to Affymetrix U133A gene chips. Genes with differential expression were identified using a permutation technique and verified by quantitative RT-PCR and im...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/sj.onc.1208285
-
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- Journal:
- Oncogene
- Volume:
- 24
- Issue:
- 7
- Pages:
- 1244-1251
- Publication date:
- 2005-02-05
- DOI:
- EISSN:
-
1476-5594
- ISSN:
-
0950-9232
- URN:
-
uuid:81e8f7bc-660a-40b1-b0a3-75ff642a2237
- Source identifiers:
-
131075
- Local pid:
- pubs:131075
- Language:
- English
- Keywords:
- Copyright date:
- 2005
Journal article
Gene expression signature predicts lymphatic metastasis in squamous cell carcinoma of the oral cavity.
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