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Journal article

Gene expression signature predicts lymphatic metastasis in squamous cell carcinoma of the oral cavity.

Abstract:

Metastasis via the lymphatics is a major risk factor in squamous cell carcinoma of the oral cavity (OSCC). We sought to determine whether the presence of metastasis in the regional lymph node could be predicted by a gene expression signature of the primary tumor. A total of 18 OSCCs were characterized for gene expression by hybridizing RNA to Affymetrix U133A gene chips. Genes with differential expression were identified using a permutation technique and verified by quantitative RT-PCR and im...

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Publication status:
Published

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Publisher copy:
10.1038/sj.onc.1208285

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Journal:
Oncogene
Volume:
24
Issue:
7
Pages:
1244-1251
Publication date:
2005-02-01
DOI:
EISSN:
1476-5594
ISSN:
0950-9232
Source identifiers:
131075

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