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An association between bacterial genotype combined with a high-vancomycin minimum inhibitory concentration and risk of endocarditis in methicillin-resistant staphylococcus aureus bloodstream infection

Abstract:

Introduction. Antimicrobial resistance and bacterial virulence factors may increase the risk of hematogenous complications during methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infection (BSI). This study reports on the impact of increasing vancomycin minimum inhibitory concentrations (V-MICs) and MRSA clone type on risk of hematogenous complications from MRSA BSI during implementation of an effective MRSA control program. Methods. In sum, spa typing, staphylococcal cassette c...

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Publisher copy:
10.1093/cid/cir858

Authors


Miller, CE More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
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Journal:
Clinical Infectious Diseases
Volume:
54
Issue:
5
Pages:
591-600
Publication date:
2012-03-01
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
URN:
uuid:81e6a667-e0c6-4751-bf52-f2e0e8da2992
Source identifiers:
342919
Local pid:
pubs:342919
Language:
English

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