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Pathogen-reduced platelets for the prevention of bleeding in people of any age

Abstract:

Clinical Question Are pathogen-reduced platelets as effective as standard platelets for the prevention of bleeding in people of any age requiring platelet transfusions?

Bottom Line In people with cancer who have a low platelet count due to their disease or its treatment, pathogen-reduced platelet transfusions increase risk of platelet refractoriness and platelet transfusion requirement (high-quality evidence) but probably do not effect all-cause mor...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1001/jamaoncol.2017.5049

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; RDM Clinical Laboratory Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; NPEU
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Role:
Author
National Institute for Health Research More from this funder
Publisher:
American Medical Association Publisher's website
Journal:
JAMA Oncology Journal website
Volume:
4
Issue:
4
Pages:
571-572
Publication date:
2018-01-25
Acceptance date:
2017-11-20
DOI:
EISSN:
2374-2445
ISSN:
2374-2437
Pubs id:
pubs:809176
URN:
uri:81e445f3-104b-49b1-a996-5e292030a330
UUID:
uuid:81e445f3-104b-49b1-a996-5e292030a330
Local pid:
pubs:809176

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