Rethinking the application of nanoparticles in women’s reproductive health and assisted reproduction

Journal article : Review

Nanoparticles and nanotechnology may present opportunities to revolutionize the prevention, treatment and diagnosis of a range of reproductive health conditions in women. These technologies are also used to improve outcomes of assisted reproductive technology. We highlight a range of these potential clinical uses of nanoparticles for polycystic ovary syndrome, endometriosis, uterine fibroids and sexually transmitted infections, considering in vitro and in vivo studies along with clinical trials. In addition, we discuss applications of nanoparticles in assisted reproductive technology, including sperm loading, gamete and embryo preservation and preventing preterm birth. Finally, we present some of the concerns associated with the medical use of nanoparticles, identifying routes for further exploration before nanoparticles can be applied to women’s reproductive health in the clinic.

Authors: Davis, EH; Jones, C; Coward, K

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Future Science Group
• Journal: Nanomedicine
• Volume: 0
• Issue: 0
• Publication date: 2024-04-30
• Acceptance date: 2024-03-25
• DOI: 10.2217/nnm-2023-0346
• EISSN: 1748-6963
• ISSN: 1743-5889
• Language: English
• Keywords: nanoparticles; uterine fibroids; polycystic ovary syndrome; assisted reproductive technology; endometriosis; women’s reproductive health; sexually transmitted infections
• Subtype: Review