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Journal article

MDM2 SNP309 associates with accelerated pancreatic adenocarcinoma formation.

Abstract:

OBJECTIVES: The G-allele of a single nucleotide polymorphism in the promoter of the MDM2 gene (MDM2 SNP309, T/G) associates with the acceleration of tumor formation and an increased risk for developing various malignancies. In this report, the possible role of the MDM2 SNP309 locus with regard to sex, age, and p53 mutational status in the development and progression of pancreatic ductal adenocarcinoma (PDAC) was examined. METHODS: One hundred three PDAC patients with comprehensive clinical, ...

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Publication status:
Published

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Journal:
Pancreas
Volume:
39
Issue:
1
Pages:
76-80
Publication date:
2010-01-05
DOI:
EISSN:
1536-4828
ISSN:
0885-3177
URN:
uuid:819d0ede-eb73-473e-868e-c0da36ec788a
Source identifiers:
69620
Local pid:
pubs:69620

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