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Journal article

Impact of intrapatient variability (IPV) in tacrolimus trough levels on long-term renal transplant function: multicentre collaborative retrospective cohort study protocol.

Abstract:

Introduction

High intrapatient variability (IPV) in tacrolimus trough levels has been shown to be associated with higher rates of renal transplant failure. There is no consensus on what level of IPV constitutes a risk of graft loss. The establishment of such a threshold could help to guide clinicians in identifying at-risk patients to receive targeted interventions to improve IPV and thus outcomes.

Methods and analysis

A multicentre Transplant Audit Collaborative ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1136/bmjopen-2017-016144

Authors


Goldsmith, PM More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
ORCID:
0000-0001-5793-4777
Okechukwu, O More by this author
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Astellas Pharma UK More from this funder
Publisher:
BMJ Open Publisher's website
Journal:
BMJ Open Journal website
Volume:
7
Issue:
7
Pages:
e016144
Publication date:
2017-07-17
Acceptance date:
2017-06-09
DOI:
EISSN:
2044-6055
Pubs id:
pubs:713274
URN:
uri:81916ee3-1134-46dc-8b4d-e65234dcbacc
UUID:
uuid:81916ee3-1134-46dc-8b4d-e65234dcbacc
Local pid:
pubs:713274

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