- Abstract:
-
We describe the characterization of sialic acid-binding Ig-like lectin-7 (siglec-7), a novel member of the siglec subgroup of the immunoglobulin superfamily. A full-length cDNA encoding siglec-7 was isolated from a human primary dendritic cell cDNA library. Siglec-7 is predicted to contain three extracellular immunoglobulin-like domains that comprise an N-terminal V-set domain and two C2-set domains, a transmembrane region and a cytoplasmic tail containing two tyrosine residues embodied in im...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1074/jbc.274.48.34089
-
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- Journal:
- The Journal of biological chemistry
- Volume:
- 274
- Issue:
- 48
- Pages:
- 34089-34095
- Publication date:
- 1999-11-05
- DOI:
- EISSN:
-
1083-351X
- ISSN:
-
0021-9258
- URN:
-
uuid:818b9d93-b610-409d-8b6b-041da58a9f54
- Source identifiers:
-
9114
- Local pid:
- pubs:9114
- Language:
- English
- Keywords:
- Copyright date:
- 1999
Journal article
Identification and characterization of a novel siglec, siglec-7, expressed by human natural killer cells and monocytes.
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