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Journal article

Identification and characterization of a novel siglec, siglec-7, expressed by human natural killer cells and monocytes.

Abstract:

We describe the characterization of sialic acid-binding Ig-like lectin-7 (siglec-7), a novel member of the siglec subgroup of the immunoglobulin superfamily. A full-length cDNA encoding siglec-7 was isolated from a human primary dendritic cell cDNA library. Siglec-7 is predicted to contain three extracellular immunoglobulin-like domains that comprise an N-terminal V-set domain and two C2-set domains, a transmembrane region and a cytoplasmic tail containing two tyrosine residues embodied in im...

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Publication status:
Published

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Publisher copy:
10.1074/jbc.274.48.34089

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division, Biomedical Research Centre
Role:
Author
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Journal:
The Journal of biological chemistry
Volume:
274
Issue:
48
Pages:
34089-34095
Publication date:
1999-11-05
DOI:
EISSN:
1083-351X
ISSN:
0021-9258
URN:
uuid:818b9d93-b610-409d-8b6b-041da58a9f54
Source identifiers:
9114
Local pid:
pubs:9114

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