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Journal article

DNA knots reveal a chiral organization of DNA in phage capsids.

Abstract:

Icosahedral bacteriophages pack their double-stranded DNA genomes to near-crystalline density and achieve one of the highest levels of DNA condensation found in nature. Despite numerous studies, some essential properties of the packaging geometry of the DNA inside the phage capsid are still unknown. We present a different approach to the problems of randomness and chirality of the packed DNA. We recently showed that most DNA molecules extracted from bacteriophage P4 are highly knotted because...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.0409323102

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Physics
Sub department:
Condensed Matter Physics
Role:
Author
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Journal:
Proceedings of the National Academy of Sciences of the United States of America More from this journal
Volume:
102
Issue:
26
Pages:
9165-9169
Publication date:
2005-06-01
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Language:
English
Keywords:
Pubs id:
pubs:154921
UUID:
uuid:8149085c-efea-4e32-8e09-a8d6c1991396
Local pid:
pubs:154921
Source identifiers:
154921
Deposit date:
2012-12-19

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