Journal article icon

Journal article

Determination of pyronaridine in whole blood by automated solid phase extraction and high-performance liquid chromatography.

Abstract:

A new extraction procedure for the analysis of pyronaridine in whole blood is presented. A weak cation exchanger with a carboxylic acid (CBA) sorbent was found to be a suitable solid phase sorbent for the extraction of pyronaridine. High-performance liquid chromatography with UV detection at 278 nm and an electrochemical detector at +0.75 V is used. The electrochemical detector gives higher selectivity than the UV detector. The separation was performed using a C18 reversed phase column with m...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Lindegårdh, N More by this author
Ericsson, O More by this author
Hellgren, U More by this author
Bergqvist, Y More by this author
Journal:
Therapeutic drug monitoring
Volume:
25
Issue:
3
Pages:
264-270
Publication date:
2003-06-05
DOI:
EISSN:
1536-3694
ISSN:
0163-4356
URN:
uuid:813e99e3-d468-48da-8ce0-a5aae3600fb8
Source identifiers:
6209
Local pid:
pubs:6209

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP