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Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.

Abstract:

Recent advances in highly multiplexed immunoassays have allowed systematic large-scale measurement of hundreds of plasma proteins in large cohort studies. In combination with genotyping, such studies offer the prospect to 1) identify mechanisms involved with regulation of protein expression in plasma, and 2) determine whether the plasma proteins are likely to be causally implicated in disease. We report here the results of genome-wide association (GWA) studies of 83 proteins considered rel...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pgen.1006706

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National Institute for Health Research More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Genetics Journal website
Volume:
13
Issue:
4
Pages:
e1006706
Publication date:
2017-04-05
Acceptance date:
2017-03-20
DOI:
ISSN:
1553-7404
Pubs id:
pubs:687891
URN:
uri:8136880d-f162-4aca-9b20-9d76439e94a6
UUID:
uuid:8136880d-f162-4aca-9b20-9d76439e94a6
Local pid:
pubs:687891
Language:
English
Keywords:

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