- Abstract:
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Recent advances in highly multiplexed immunoassays have allowed systematic large-scale measurement of hundreds of plasma proteins in large cohort studies. In combination with genotyping, such studies offer the prospect to 1) identify mechanisms involved with regulation of protein expression in plasma, and 2) determine whether the plasma proteins are likely to be causally implicated in disease. We report here the results of genome-wide association (GWA) studies of 83 proteins considered rel...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 2.5MB)
-
- Publisher copy:
- 10.1371/journal.pgen.1006706
-
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Genetics Journal website
- Volume:
- 13
- Issue:
- 4
- Pages:
- e1006706
- Publication date:
- 2017-04-05
- Acceptance date:
- 2017-03-20
- DOI:
- ISSN:
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1553-7404
- Pubs id:
-
pubs:687891
- URN:
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uri:8136880d-f162-4aca-9b20-9d76439e94a6
- UUID:
-
uuid:8136880d-f162-4aca-9b20-9d76439e94a6
- Local pid:
- pubs:687891
- Language:
- English
- Keywords:
- Copyright holder:
- Folkersen et al
- Copyright date:
- 2017
- Notes:
- © 2017 Folkersen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.
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National Institute for Health Research
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