- Abstract:
-
iPSCs (induced pluripotent stem cells) offer an unparalleled opportunity to generate and study physiologically relevant cell types in culture. iPSCs can be generated by reprogramming almost any somatic cell type using pluripotency factors such as Oct4, SOX2, Nanog and Klf4. By reprogramming cells from patients carrying disease-associated mutations, and subsequent differentiation into the cell type of interest, researchers now have the opportunity to study disease-specific cell types which wer...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1042/bst20120159
-
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- Journal:
- Biochemical Society transactions
- Volume:
- 40
- Issue:
- 5
- Pages:
- 1152-1157
- Publication date:
- 2012-10-05
- DOI:
- EISSN:
-
1470-8752
- ISSN:
-
0300-5127
- URN:
-
uuid:80fe2d1e-f11d-4a39-a14c-58bc6e2dc2dc
- Source identifiers:
-
352475
- Local pid:
- pubs:352475
- Language:
- English
- Keywords:
- Copyright date:
- 2012
Journal article
Cellular reprogramming: a new approach to modelling Parkinson's disease.
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