Journal article
Cellular reprogramming: a new approach to modelling Parkinson's disease.
- Abstract:
-
iPSCs (induced pluripotent stem cells) offer an unparalleled opportunity to generate and study physiologically relevant cell types in culture. iPSCs can be generated by reprogramming almost any somatic cell type using pluripotency factors such as Oct4, SOX2, Nanog and Klf4. By reprogramming cells from patients carrying disease-associated mutations, and subsequent differentiation into the cell type of interest, researchers now have the opportunity to study disease-specific cell types which wer...
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- Publication status:
- Published
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- Publisher copy:
- 10.1042/bst20120159
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Authors
Bibliographic Details
- Journal:
- Biochemical Society transactions
- Volume:
- 40
- Issue:
- 5
- Pages:
- 1152-1157
- Publication date:
- 2012-10-01
- DOI:
- EISSN:
-
1470-8752
- ISSN:
-
0300-5127
- Source identifiers:
-
352475
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:352475
- UUID:
-
uuid:80fe2d1e-f11d-4a39-a14c-58bc6e2dc2dc
- Local pid:
- pubs:352475
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2012
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