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Journal article

Monocyte recruitment in venous thrombus resolution.

Abstract:

OBJECTIVE: To investigate the importance of monocyte recruitment in thrombus resolution and the role of cysteine-cysteine (CC) chemokines and the CC chemokine receptor, CCR2, in this process. METHODS: Peritoneal macrophages, monocyte chemotactic protein 1 (MCP1), or carrier solutions were injected into thrombi induced in the vena cava of rats. Caval thrombi were also formed in CCR2-/- and MCP1-/- mice and in wild-type mice transfected with an adenoviral construct expressing a broad-spectrum ...

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Publication status:
Published

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Publisher copy:
10.1016/j.jvs.2005.10.073

Authors


Humphries, J More by this author
Burnand, K More by this author
Bursill, C More by this author
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Journal:
Journal of vascular surgery
Volume:
43
Issue:
3
Pages:
601-608
Publication date:
2006-03-05
DOI:
EISSN:
1097-6809
ISSN:
0741-5214
URN:
uuid:80e4ba67-ff28-45fd-825a-111bc62c3243
Source identifiers:
105008
Local pid:
pubs:105008

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