Journal article icon

Journal article

Short asymmetric syntheses of bioactive beta-aryl ethanolamine derivatives via the highly diastereoselective delta lactol oxy-Michael addition

Abstract:
Short, stereoselective and efficient total syntheses of the bioactive β-aryl ethanolamine derivatives (R)-tembamide, (R)-aegeline and (R)-pronethalol have been achieved using the highly diastereoselective oxy-Michael addition of 'naked' delta lactol anions to nitro olefins as the key step. © 2003 Elsevier Ltd. All rights reserved.
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Role:
Author
Journal:
TETRAHEDRON-ASYMMETRY
Volume:
15
Issue:
2
Pages:
195-197
Publication date:
2004-01-26
DOI:
ISSN:
0957-4166
URN:
uuid:80e3c796-6daa-4d43-94b5-57303ea6d898
Source identifiers:
52078
Local pid:
pubs:52078
Language:
English

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP