Journal article
Multiscale modelling of vascular tumour growth in 3D: the roles of domain size & boundary condition
- Abstract:
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We investigate a three-dimensional multiscale model of vascular tumour growth, which couples blood flow, angiogenesis, vascular remodelling, nutrient/growth factor transport, movement of, and interactions between, normal and tumour cells, and nutrient-dependent cell cycle dynamics within each cell. In particular, we determine how the domain size, aspect ratio and initial vascular network influence the tumour's growth dynamics and its long-time composition. We establish whether it is possible ...
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Bibliographic Details
- Publisher:
- PLOs One
- Publication date:
- 2011-01-01
Item Description
- UUID:
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uuid:807f22ad-5f84-4812-89f3-bfe22fb08b0e
- Local pid:
- oai:eprints.maths.ox.ac.uk:1057
- Deposit date:
- 2011-05-20
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- Copyright date:
- 2011
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