- Abstract:
-
PURPOSE: To develop a reproducible laboratory model to simulate a battlefield foveal laser injury and to test potential neuroprotective effects of a single injection treatment that might be administered in a military setting. METHODS: Frequency-doubled 532-nm Nd:YAG laser was used to induce a threshold retinal injury bilaterally in transgenic reporter mice that have fluorescent cones. Intravitreal injection of ciliary neurotrophic factor (CNTF) was then administered to the lasered eye and co...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1167/iovs.13-11623
-
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- Journal:
- Investigative ophthalmology and visual science
- Volume:
- 54
- Issue:
- 8
- Pages:
- 5456-5465
- Publication date:
- 2013-08-05
- DOI:
- EISSN:
-
1552-5783
- ISSN:
-
0146-0404
- URN:
-
uuid:8061c44d-c647-4b9c-bb43-796fe64bb62d
- Source identifiers:
-
401915
- Local pid:
- pubs:401915
- Language:
- English
- Keywords:
- Copyright date:
- 2013
Journal article
Cone photoreceptor neuroprotection conferred by CNTF in a novel in vivo model of battlefield retinal laser injury.
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