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Journal article

Tumor necrosis factor SNP haplotypes are associated with iron deficiency anemia in West African children.

Abstract:

Plasma levels of tumor necrosis factor-alpha (TNF-alpha) are significantly raised in malaria infection and TNF-alpha is thought to inhibit intestinal iron absorption and macrophage iron release. This study investigated putative functional single nucleotide polymorphisms (SNPs) and haplotypes across the major histocompatibility complex (MHC) class III region, including TNF and its immediate neighbors nuclear factor of kappa light polypeptide gene enhancer in B cells (lkappaBL), inhibitor-like ...

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Publication status:
Published

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Journal:
Blood
Volume:
112
Issue:
10
Pages:
4276-4283
Publication date:
2008-11-05
DOI:
EISSN:
1528-0020
ISSN:
0006-4971
URN:
uuid:804ebe40-f449-4667-ad64-de8c821c8d34
Source identifiers:
40983
Local pid:
pubs:40983

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