- Abstract:
-
Thioglycollate-stimulated murine peritoneal macrophages were cultured for eight days in the presence of swainsonine, or 1,4-dideoxy-1,4-imino-D-mannitol (DIM), or both of these competitive alpha-mannosidase inhibitors together. Analysis of accumulated high-mannose oligosaccharides by reversed phase HPLC after perbenzoylation revealed that DIM- and DIM-plus swainsonine-treated macrophages contained larger amounts of Man7GlcNAc, Man8GlcNAc and Man9GlcNAc, while swainsonine-treated macrophages c...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1007/bf01050651
-
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- Journal:
- Glycoconjugate journal
- Volume:
- 6
- Issue:
- 2
- Pages:
- 229-240
- Publication date:
- 1989-01-01
- DOI:
- EISSN:
-
1573-4986
- ISSN:
-
0282-0080
- URN:
-
uuid:80241565-7e8d-4c92-b73b-7a98f04efa9c
- Source identifiers:
-
43071
- Local pid:
- pubs:43071
- Language:
- English
- Keywords:
- Copyright date:
- 1989
Journal article
Effects of the alpha-mannosidase inhibitors, 1,4-dideoxy-1,4-imino-D-mannitol and swainsonine, on glycoprotein catabolism in cultured macrophages.
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