Journal article icon

Journal article

The pharmacokinetics of atovaquone and proguanil in pregnant women with acute falciparum malaria.

Abstract:

OBJECTIVE: To determine the pharmacokinetic properties of atovaquone, proguanil, and the triazine metabolite cycloguanil in women with recrudescent multi-drug resistant falciparum malaria during the second and third trimesters of pregnancy treated by artesunate-atovaquone-proguanil. METHODS: Serial plasma concentrations of atovaquone, proguanil and cycloguanil were measured in 24 women at baseline and after the final dose of the 3-day treatment with atovaquone (20 mg/kg/day) plus proguanil (...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1007/s00228-003-0652-9

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Journal:
European journal of clinical pharmacology
Volume:
59
Issue:
7
Pages:
545-552
Publication date:
2003-10-01
DOI:
EISSN:
1432-1041
ISSN:
0031-6970

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP