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The role of metabolite-sensing G protein-coupled receptors in inflammation and metabolic disease

Abstract:
Significance: Great attention has been placed on the link between metabolism and immune function giving rise to the term “immunometabolism.” It is widely accepted that inflammation and oxidative stress are key processes that underlie metabolic complications during obesity, diabetes, and atherosclerosis. Therefore, identifying the mechanisms and mediators that are involved in the regulation of both inflammation and metabolic homeostasis is of high scientific and therapeutic in... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1089/ars.2017.7168

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
ORCID:
0000-0002-3224-3651
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
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Publisher:
Mary Ann Liebert Publisher's website
Journal:
Antioxidants and Redox Signaling Journal website
Volume:
29
Issue:
3
Pages:
237-256
Publication date:
2018-01-17
Acceptance date:
2017-11-04
DOI:
EISSN:
1557-7716
ISSN:
1523-0864
Pubs id:
pubs:745983
URN:
uri:7fd2c9b9-de30-46ea-b981-55a941b3ff23
UUID:
uuid:7fd2c9b9-de30-46ea-b981-55a941b3ff23
Local pid:
pubs:745983

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