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Effect of statins on ventricular tachyarrhythmia, cardiac arrest, and sudden cardiac death: a meta-analysis of published and unpublished evidence from randomized trials.

Abstract:

AIMS: The effect of statin treatment on ventricular arrhythmic complications is uncertain. We sought to test whether statins reduce the risk of ventricular tachyarrhythmia, cardiac arrest, and sudden cardiac death. METHODS AND RESULTS: We searched MEDLINE, EMBASE, and CENTRAL up to October 2010. Randomized controlled trials comparing statin with no statin or comparing intensive vs. standard dose statin, with more than 100 participants and at least 6-month follow-up were considered for inclus...

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Publication status:
Published

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Publisher copy:
10.1093/eurheartj/ehs005

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine, Population Health
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit, BHF Centre of Research Excellence
Journal:
European heart journal
Volume:
33
Issue:
13
Pages:
1571-1581
Publication date:
2012-07-05
DOI:
EISSN:
1522-9645
ISSN:
0195-668X
URN:
uuid:7fd212e6-743f-427d-865c-4fc953ed2415
Source identifiers:
267829
Local pid:
pubs:267829

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