Journal article icon

Journal article

Anxious, hypoactive phenotype combined with motor deficits in Gtf2ird1 null mouse model relevant to Williams syndrome.

Abstract:

Williams-Beuren syndrome (WBS) is a rare genetic disorder caused by a hemizygous deletion of around 28 genes on the long arm of chromosome 7 (7q11.23), characterized by a unique spectrum of behavioral impairments, including mental retardation, deficits in visuospatial constructive cognition, hypersociability, anxiety and simple phobias. Physical characteristics include dysmorphic faces, short stature, oculomotor deficits, gross and fine coordination impairments, diminished control of balance ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1016/j.bbr.2012.05.014

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
Expand authors...
Journal:
Behavioural brain research
Volume:
233
Issue:
2
Pages:
458-473
Publication date:
2012-08-05
DOI:
EISSN:
1872-7549
ISSN:
0166-4328
URN:
uuid:7fc5f5bc-2c38-4736-a2fa-9d09ee87a10f
Source identifiers:
334712
Local pid:
pubs:334712

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP