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Journal article

Anxious, hypoactive phenotype combined with motor deficits in Gtf2ird1 null mouse model relevant to Williams syndrome.

Abstract:

Williams-Beuren syndrome (WBS) is a rare genetic disorder caused by a hemizygous deletion of around 28 genes on the long arm of chromosome 7 (7q11.23), characterized by a unique spectrum of behavioral impairments, including mental retardation, deficits in visuospatial constructive cognition, hypersociability, anxiety and simple phobias. Physical characteristics include dysmorphic faces, short stature, oculomotor deficits, gross and fine coordination impairments, diminished control of balance ...

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Publication status:
Published

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Publisher copy:
10.1016/j.bbr.2012.05.014

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
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Journal:
Behavioural brain research
Volume:
233
Issue:
2
Pages:
458-473
Publication date:
2012-08-01
DOI:
EISSN:
1872-7549
ISSN:
0166-4328
Source identifiers:
334712

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