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Glycosyl-phosphatidylinositol molecules of the parasite and the host.

Abstract:

The glycosyl-phosphatidylinositol (GPI) protein-membrane anchors are ubiquitous among the eukaryotes. However, while mammalian cells typically express in the order of 100 thousand copies of GPI-anchor per cell, the parasitic protozoa, particularly the kinetoplastids, express up to 10-20 million copies of GPI-anchor and/or GPI-related glycolipids per cell. Thus GPI-family members dominate the cell surface molecular architecture of these organisms. In several cases, GPI-anchored proteins, such ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1017/s0031182000075715

Authors


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Wellcome Trust More from this funder
Science and Engineering Research Council More from this funder
Publisher:
Cambridge University Press Publisher's website
Journal:
Parasitology Journal website
Volume:
108 Suppl
Issue:
SUPPL.
Pages:
S45-S54
Publication date:
1994-04-06
DOI:
EISSN:
1469-8161
ISSN:
0031-1820
URN:
uuid:7f9aacba-a3d9-40e2-aefa-87dfb7516180
Source identifiers:
207624
Local pid:
pubs:207624

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