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Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem

Abstract:

Cajal-Retzius (CR) cells play a crucial role in the formation of the cerebral cortex, yet the molecules that control their development are largely unknown. Here, we show that Ebf transcription factors are expressed in forebrain signalling centres-the septum, cortical hem and the pallial-subpallial boundary-known to generate CR cells. We identified Ebf2, through fate mapping studies, as a novel marker for cortical hem- and septum-derived CR cells. Loss of Ebf2 in vivo causes a transient decrea...

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Publisher copy:
10.1016/j.ydbio.2012.02.034

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Journal:
Developmental Biology
Volume:
365
Issue:
1
Pages:
277-289
Publication date:
2012-05-01
DOI:
EISSN:
1095-564X
ISSN:
0012-1606
URN:
uuid:7f4ebb34-ad44-482b-96a2-6a6c5e5f9881
Source identifiers:
323470
Local pid:
pubs:323470
Language:
English
Keywords:

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