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Journal article

Drosophila patterning is established by differential association of mRNAs with P bodies.

Abstract:

The primary embryonic axes in flies, frogs and fish are formed through translational regulation of localized transcripts before fertilization. In Drosophila melanogaster, the axes are established through the transport and translational regulation of gurken (grk) and bicoid (bcd) messenger RNA in the oocyte and embryo. Both transcripts are translationally silent while being localized within the oocyte along microtubules by cytoplasmic dynein. Once localized, grk is translated at the dorsoanter...

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Publication status:
Published

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Publisher copy:
10.1038/ncb2627

Authors


Parton, RM More by this author
Herpers, B More by this author
Soetaert, J More by this author
Veenendaal, T More by this author
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Journal:
Nature cell biology
Volume:
14
Issue:
12
Pages:
1305-1313
Publication date:
2012-12-05
DOI:
EISSN:
1476-4679
ISSN:
1465-7392
URN:
uuid:7f1c9c72-a676-4c62-ae95-de8909e28f00
Source identifiers:
365519
Local pid:
pubs:365519

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