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Journal article

Fragment-based hit identification: thinking in 3D.

Abstract:

The identification of high-quality hits during the early phases of drug discovery is essential if projects are to have a realistic chance of progressing into clinical development and delivering marketed drugs. As the pharmaceutical industry goes through unprecedented change, there are increasing opportunities to collaborate via pre-competitive networks to marshal multifunctional resources and knowledge to drive impactful, innovative science. The 3D Fragment Consortium is developing fragment-s...

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Publication status:
Published

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Authors


Morley, AD More by this author
Pugliese, A More by this author
Birchall, K More by this author
Brennan, P More by this author
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Journal:
Drug discovery today
Volume:
18
Issue:
23-24
Pages:
1221-1227
Publication date:
2013-12-05
DOI:
EISSN:
1878-5832
ISSN:
1359-6446
URN:
uuid:7f134519-ccd3-4ec8-aabd-eef5f8a5d859
Source identifiers:
447482
Local pid:
pubs:447482
Language:
English

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