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Association between endometriosis and the interleukin 1A (IL1A) locus.

Abstract:

STUDY QUESTION: Are single-nucleotide polymorphisms (SNPs) at the interleukin 1A (IL1A) gene locus associated with endometriosis risk? SUMMARY ANSWER: We found evidence for strong association between IL1A SNPs and endometriosis risk. WHAT IS KNOWN ALREADY: Genetic factors contribute substantially to the complex aetiology of endometriosis and the disease has an estimated heritability of ∼51%. We, and others, have conducted genome-wide association (GWA) studies for endometriosis, which identifi...

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Publisher copy:
10.1093/humrep/deu267

Authors


Sapkota, Y More by this author
Gordon, SD More by this author
Henders, AK More by this author
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Journal:
Human reproduction (Oxford, England)
Volume:
30
Issue:
1
Pages:
239-248
Publication date:
2015-01-05
DOI:
EISSN:
1460-2350
ISSN:
0268-1161
URN:
uuid:7ec86a03-e19a-4852-991a-10e8b1e61bde
Source identifiers:
488416
Local pid:
pubs:488416

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