The PTS(Ntr) system globally regulates ATP-dependent transporters in Rhizobium leguminosarum.

Journal article

Mutation of ptsP encoding EI(Ntr) of the PTS(Ntr) system in Rhizobium leguminosarum strain Rlv3841 caused a pleiotropic phenotype as observed with many bacteria. The mutant formed dry colonies and grew poorly on organic nitrogen or dicarboxylates. Most strikingly the ptsP mutant had low activity of a broad range of ATP-dependent ABC transporters. This lack of activation, which occurred post-translationally, may explain many of the pleiotropic effects. In contrast proton-coupled transport sy...

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Authors: Prell, J; Mulley, G; Haufe, F; White, J; Williams, A

• Journal: Molecular microbiology
• Volume: 84
• Issue: 1
• Pages: 117-129
• Publication date: 2012-04-01
• DOI: 10.1111/j.1365-2958.2012.08014.x
• EISSN: 1365-2958
• ISSN: 0950-382X
• Language: English
• Keywords: Gene Expression Regulation, Bacterial; Phosphorylation; ATP-Binding Cassette Transporters; Biological Transport; Homeostasis; Bacterial Proteins; Potassium; Mutation; Rhizobium leguminosarum; Phosphoenolpyruvate Sugar Phosphotransferase System; Transcriptional Activation; Protein Kinases