Journal article icon

Journal article

Cytomegalovirus reinfections stimulate CD8 T-memory inflation

Abstract:

Cytomegalovirus (CMV) has been shown to induce large populations of CD8 T-effector memory cells that unlike central memory persist in large quantities following infection, a phenomenon commonly termed “memory inflation”. Although murine models to date have shown very large and persistent CMV-specific T-cell expansions following infection, there is considerable variability in CMV-specific T-memory responses in humans. Historically such memory inflation in humans has been assumed a consequence ...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pone.0167097

Authors


Expand authors...
More from this funder
Grant:
NIGMS, Grant Number GM066115
Publisher:
Public Library of Science Publisher's website
Journal:
PLOS One Journal website
Publication date:
2016-11-21
Acceptance date:
2016-11-08
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Pubs id:
pubs:661780
URN:
uri:7e95a022-bd88-470b-8768-8788f46fd181
UUID:
uuid:7e95a022-bd88-470b-8768-8788f46fd181
Local pid:
pubs:661780

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP