Journal article

A short stereoselective total synthesis of the fusarium toxin equisetin.

Abstract:: A short stereoselective synthesis of the fusarium toxin equisetin, an N-methylserine-derived acyl tetramic acid and potent inhibitor of HIV-1 integrase enzyme, is described using as the key step a stereoselective lithium perchlorate mediated intramolecular Diels-Alder reaction of a fully conjugated E,E,E-triene with a trisubstituted gamma,delta-unsaturated beta-ketothioester.

Publication status:: Published

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APA Style

Burke, L. T., Dixon, D., Ley, S., & Rodríguez, F. (2000). A short stereoselective total synthesis of the fusarium toxin equisetin. Organic Letters, 2(23), 3611–3613.

MLA Style

Burke, L. T., et al. “A Short Stereoselective Total Synthesis of the Fusarium Toxin Equisetin.” Organic Letters, vol. 2, no. 23, 2000, pp. 3611–13.

Chicago Style

Burke, LT, D Dixon, S Ley, and F Rodríguez. 2000. “A Short Stereoselective Total Synthesis of the Fusarium Toxin Equisetin.” Organic Letters 2 (23): 3611–13.
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Publisher copy:: 10.1021/ol006493u

Authors

+ Burke, LT More by this author

Role:: Author

+ Dixon, D More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

+ Ley, S More by this author

Role:: Author

+ Rodríguez, F More by this author

Role:: Author

Journal:: Organic letters More from this journal
Volume:: 2
Issue:: 23
Pages:: 3611-3613
Publication date:: 2000-11-01
DOI:: 10.1021/ol006493u
EISSN:: 1523-7052
ISSN:: 1523-7060

Language:: English
Keywords:: HIV-1

Stereoisomerism

Fusarium

HIV Integrase Inhibitors

Pyrrolidinones

HIV Protease Inhibitors

Indicators and Reagents

Tetrahydronaphthalenes

Acetylation
Pubs id:: pubs:52045
UUID:: uuid:7e344d90-a38f-4fed-8081-0db4c9f3d297
Local pid:: pubs:52045
Source identifiers:: 52045
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2000

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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