There is growing evidence for exaggerated oscillatory neuronal synchronisation in patients with Parkinson's disease (PD). In particular, oscillations at around 20 Hz, in the so-called beta frequency band, relate to the cardinal symptoms of bradykinesia and rigidity. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) can significantly improve these motor impairments. Recent evidence has demonstrated reduction of beta oscillations concurrent with alleviation of PD motor symptoms, rai...Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
- Publisher's Version
- Frontiers Media Publisher's website
- Frontiers in Integrative Neuroscience Journal website
- July 2012
- Publication date:
- Acceptance date:
- Source identifiers:
- Local pid:
- Copyright holder:
- Eusebio, et al.
- Copyright date:
- Copyright © 2012 Eusebio, Cagnan and Brown. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
Does suppression of oscillatory synchronisation mediate some of the therapeutic effects of DBS in patients with Parkinson's disease?
If you are the owner of this record, you can report an update to it here: Report update to this record