Journal article
Does suppression of oscillatory synchronisation mediate some of the therapeutic effects of DBS in patients with Parkinson's disease?
- Abstract:
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There is growing evidence for exaggerated oscillatory neuronal synchronisation in patients with Parkinson's disease (PD). In particular, oscillations at around 20 Hz, in the so-called beta frequency band, relate to the cardinal symptoms of bradykinesia and rigidity. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) can significantly improve these motor impairments. Recent evidence has demonstrated reduction of beta oscillations concurrent with alleviation of PD motor symptoms, rai...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 575.8KB)
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- Publisher copy:
- 10.3389/fnint.2012.00047
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Authors
Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Integrative Neuroscience Journal website
- Volume:
- 6
- Issue:
- July 2012
- Pages:
- 47
- Publication date:
- 2012-07-10
- Acceptance date:
- 2012-06-25
- DOI:
- EISSN:
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1662-5145
- ISSN:
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1662-5145
- Source identifiers:
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342481
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:7e07d259-f69b-43c1-9492-94b9326500c6
- Local pid:
- pubs:342481
- Deposit date:
- 2014-06-24
Terms of use
- Copyright holder:
- Eusebio, et al
- Copyright date:
- 2012
- Notes:
- Copyright © 2012 Eusebio, Cagnan and Brown. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
- Licence:
- CC Attribution (CC BY)
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