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Evidence for genetic regulation of vitamin D status in twins with multiple sclerosis.

Abstract:

BACKGROUND: Multiple sclerosis (MS) risk is determined by both genes and environment. One of the most striking features of MS is its geographic distribution, particularly the pattern of high MS frequency in areas with low sunlight exposure, the main inducer of vitamin D synthesis. Recent epidemiologic, experimental, and clinical evidence support an effect for low environmental supplies of vitamin D in mediating an increased susceptibility to MS. OBJECTIVES: We 1) examined the association of ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Herrera, BM More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Lincoln, MR More by this author
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Journal:
The American journal of clinical nutrition
Volume:
88
Issue:
2
Pages:
441-447
Publication date:
2008-08-05
EISSN:
1938-3207
ISSN:
0002-9165
URN:
uuid:7df96564-5305-463d-a92c-23c33ba4ba8c
Source identifiers:
34347
Local pid:
pubs:34347

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