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Evasion of macrophage scavenger receptor A-mediated recognition by pathogenic streptococci.

Abstract:

PRR recognize conserved structures on pathogenic microbes and are important for the defense against invading microorganisms. However, accumulating evidence indicates that many pathogens have evolved mechanisms to avoid recognition by PRR. One type of PRR is the macrophage scavenger receptor A (SR-A), which has been shown to play an important role in recognition and non-opsonic phagocytosis of pathogenic bacteria. The bacterial ligands for SR-A have been suggested to be LPS or lipoteichoic aci...

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Publication status:
Published

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Publisher copy:
10.1002/eji.200838457

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
European journal of immunology
Volume:
38
Issue:
11
Pages:
3068-3079
Publication date:
2008-11-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:7de9b18c-6f5b-491d-baed-970cb02176a7
Source identifiers:
16901
Local pid:
pubs:16901

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