- Abstract:
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Background: Statin therapy is effective for the prevention of coronary heart disease and stroke in patients with mild-to-moderate chronic kidney disease, but its effects in individuals with more advanced disease, particularly those undergoing dialysis, are uncertain. Methods: We did a meta-analysis of individual participant data from 28 trials (n=183 419), examining effects of statin-based therapy on major vascular events (major coronary event [non-fatal m... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 312.9kb)
-
- Publisher copy:
- 10.1016/S2213-8587(16)30156-5
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- Publisher:
- Elsevier Publisher's website
- Journal:
- Lancet Diabetes and Endocrinology Journal website
- Volume:
- 4
- Issue:
- 10
- Pages:
- 829–839
- Acceptance date:
- 2016-06-23
- DOI:
- EISSN:
-
2213-8595
- ISSN:
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2213-8587
- Pubs id:
-
pubs:637374
- URN:
-
uri:7dbdb6a9-d8bf-42bc-bf66-db346e75dc5e
- UUID:
-
7dbdb6a9-d8bf-42bc-bf66-db346e75dc5e
- Local pid:
- pubs:637374
- Paper number:
- 10
- Copyright holder:
- CTT Collaboration
- Notes:
- Copyright © The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license.
Journal article
Impact of renal function on the effects of LDL cholesterol lowering with statin-based regimens: a meta-analysis of individual participant data from 28 randomised trials
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Medical Research Council
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British Heart Foundation
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Cancer Research UK
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Australian National Health and Medical Research Council
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