Journal article
Impact of renal function on the effects of LDL cholesterol lowering with statin-based regimens: a meta-analysis of individual participant data from 28 randomised trials
- Abstract:
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Background: Statin therapy is effective for the prevention of coronary heart disease and stroke in patients with mild-to-moderate chronic kidney disease, but its effects in individuals with more advanced disease, particularly those undergoing dialysis, are uncertain. Methods: We did a meta-analysis of individual participant data from 28 trials (n=183 419), examining effects of statin-based therapy on major vascular events (major coronary event [non-fatal m... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 312.9KB)
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- Publisher copy:
- 10.1016/S2213-8587(16)30156-5
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Authors
Funding
Cancer Research UK
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Australian National Health and Medical Research Council
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Australian National Heart Foundation
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Medical Research Council
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Lancet Diabetes and Endocrinology Journal website
- Volume:
- 4
- Issue:
- 10
- Pages:
- 829–839
- Publication date:
- 2016-07-29
- Acceptance date:
- 2016-06-23
- DOI:
- EISSN:
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2213-8595
- ISSN:
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2213-8587
- Source identifiers:
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637374
Item Description
- Pubs id:
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pubs:637374
- UUID:
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uuid:7dbdb6a9-d8bf-42bc-bf66-db346e75dc5e
- Local pid:
- pubs:637374
- Deposit date:
- 2016-10-12
Terms of use
- Copyright holder:
- CTT Collaboration
- Copyright date:
- 2016
- Notes:
- Copyright © The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license.
- Licence:
- CC Attribution (CC BY)
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