- Abstract:
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The indigenous people of the Tibetan Plateau have been the subject of much recent interest because of their unique genetic adaptations to high altitude. Recent studies have demonstrated that the Tibetan EPAS1 haplotype is involved in high altitude-adaptation and originated in an archaic Denisovan-related population. We sequenced the whole-genomes of 27 Tibetans and conducted analyses to infer a detailed history of demography and natural selection of this population. We detected evidence of po...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 1.9MB)
-
- Publisher copy:
- 10.1371/journal.pgen.1006675
-
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Genetics Journal website
- Volume:
- 13
- Issue:
- 4
- Pages:
- e1006675
- Publication date:
- 2017-04-05
- Acceptance date:
- 2017-03-08
- DOI:
- EISSN:
-
1553-7404
- ISSN:
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1553-7390
- Pubs id:
-
pubs:692374
- URN:
-
uri:7d98a200-64ac-44cb-97fc-6ee52cbf983b
- UUID:
-
uuid:7d98a200-64ac-44cb-97fc-6ee52cbf983b
- Local pid:
- pubs:692374
- Language:
- English
- Keywords:
- Copyright holder:
- Hu et al
- Copyright date:
- 2017
- Notes:
- © 2017 Hu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
Evolutionary history of Tibetans inferred from whole-genome sequencing.
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University of Luxembourg
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