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Time-correlated single-photon counting fluorescence lifetime confocal imaging of decayed and sound dental structures with a white-light supercontinuum source.

Abstract:

We report the demonstration of time-correlated single-photon counting (TCSPC) fluorescence lifetime imaging (FLIM) to ex vivo decayed and healthy dentinal tooth structures, using a white-light supercontinuum excitation source. By using a 100 fs-pulsed Ti:Sapphire laser with a low-frequency chirp to pump a 30-cm long section of photonic crystal fibre, a ps-pulsed white-light supercontinuum was created. Optical bandpass interference filters were then applied to this broad-bandwidth source to se...

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Publication status:
Published

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Authors


McConnell, G More by this author
Girkin, JM More by this author
Ameer-Beg, SM More by this author
Barber, PR More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
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Journal:
Journal of microscopy
Volume:
225
Issue:
Pt 2
Pages:
126-136
Publication date:
2007-02-05
DOI:
EISSN:
1365-2818
ISSN:
0022-2720
URN:
uuid:7d79a0b8-af68-46c4-99e1-5ca7ae30e6ef
Source identifiers:
130933
Local pid:
pubs:130933

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