Journal article icon

Journal article

Genetic modification of dendritic cells through the directed differentiation of embryonic stem cells.

Abstract:

Recent years have witnessed a progressive acceptance of the dual role played by dendritic cells (DC) in the initiation of immune responses and their specific attenuation through the induction of immunological tolerance. Nevertheless, as terminally differentiated cells of the myeloid lineage, DC share with macrophages an inherent resistance to genetic modification, greatly restricting strategies available for studying their physiology and function. Consequently, little is known of the molecula...

Expand abstract

Actions


Access Document


Publisher copy:
10.1007/978-1-59745-395-0_4

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Methods in molecular biology (Clifton, N.J.)
Volume:
380
Pages:
59-72
Publication date:
2007-01-01
DOI:
EISSN:
1940-6029
ISSN:
1064-3745
Source identifiers:
4385
Language:
English
Keywords:
Pubs id:
pubs:4385
UUID:
uuid:7d687a13-29c5-448b-ab6c-76da32bbd063
Local pid:
pubs:4385
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP