Journal article
Porcine islet graft function is affected by pretreatment with a caspase-3 inhibitor.
- Abstract:
-
During the isolation procedure and after transplantation islets are subjected to numerous variables associated with the induction of apoptosis. The present study investigated the effect of transient pretreatment with caspase inhibitors on function and survival of transplanted pig islets. Isolated porcine islets (3000 IEQ) were incubated overnight in 200 microM of the caspase-3 inhibitor DEVD-CMK prior to transplantation into diabetic nude mice. Glucose-stimulated insulin release of pretreated...
Expand abstract
Actions
Authors
Bibliographic Details
- Journal:
- Cell transplantation
- Volume:
- 15
- Issue:
- 4
- Pages:
- 311-317
- Publication date:
- 2006-01-01
- DOI:
- EISSN:
-
1555-3892
- ISSN:
-
0963-6897
- Source identifiers:
-
266499
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:266499
- UUID:
-
uuid:7d47e67c-fd34-4971-8431-fd0612a94028
- Local pid:
- pubs:266499
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2006
If you are the owner of this record, you can report an update to it here: Report update to this record