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Tenofovir disoproxil fumarate fails to prevent HIV acquisition or the establishment of a viral reservoir: two case reports

Abstract:

The use of antiretrovirals as pre-exposure prophylaxis (PrEP) is highly efficacious in HIV prevention. The World Health Organization recently recommended Truvada(®) (Gilead Sciences, Inc.) or tenofovir disoproxil fumarate (TDF) for high-risk individuals, with limited data for single-agent TDF PrEP in men who have sex with men (MSM). We report two cases of TDF PrEP failure in MSM who had received long-term TDF for hepatitis B infection and had therapeutic levels of drug immediately after HIV a...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1007/s40121-015-0102-x

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Publisher:
Springer Healthcare Publisher's website
Journal:
Infectious diseases and therapy Journal website
Volume:
5
Issue:
1
Pages:
65-71
Publication date:
2016-01-09
DOI:
EISSN:
2193-6382
ISSN:
2193-8229
URN:
uuid:7d0fd7c2-dd01-475a-b9fd-ea3f557da2db
Source identifiers:
587536
Local pid:
pubs:587536
Paper number:
1

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