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Journal article

Fractionation effects in particle radiotherapy: implications for hypo-fractionation regimes.

Abstract:

The aim is to demonstrate the potential impact of changes in the value of the β parameter in the linear quadratic (LQ) model on the calculation of clinical relative biological effectiveness (RBE) values used for high linear energy transfer (LET) radiotherapy. The parameter RBE(min) is introduced into the LQ formulation to account for possible changes in the β radiosensitivity coefficient with changing LET. The model is used to fit fractionated data under two conditions, where RBE(min) = 1 and...

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Publication status:
Published

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Publisher copy:
10.1088/0031-9155/55/19/005

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
Journal:
Physics in medicine and biology
Volume:
55
Issue:
19
Pages:
5685-5700
Publication date:
2010-10-01
DOI:
EISSN:
1361-6560
ISSN:
0031-9155
Source identifiers:
132319
Language:
English
Keywords:
Pubs id:
pubs:132319
UUID:
uuid:7d0bec78-fae1-4a72-a9d8-87b7f2a6d200
Local pid:
pubs:132319
Deposit date:
2012-12-19

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