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Journal article

A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion.

Abstract:

Integrin-linked kinase (ILK) has been implicated in the regulation of a range of fundamental biological processes such as cell survival, growth, differentiation, and adhesion. In platelets ILK associates with beta1- and beta3-containing integrins, which are of paramount importance for the function of platelets. Upon stimulation of platelets this association with the integrins is increased and ILK kinase activity is up-regulated, suggesting that ILK may be important for the coordination of pla...

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Publication status:
Published

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Authors


Tucker, KL More by this author
Stevens, JM More by this author
Jordan, PA More by this author
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Journal:
Blood
Volume:
112
Issue:
12
Pages:
4523-4531
Publication date:
2008-12-05
DOI:
EISSN:
1528-0020
ISSN:
0006-4971
URN:
uuid:7d086be3-2dc7-409e-b00b-5f22a4f3d94e
Source identifiers:
244376
Local pid:
pubs:244376

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