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Journal article : Review

Morphogen signals shaping the gastric glands in health and disease

Abstract:

The adult gastric mucosa is characterised by deep invaginations of the epithelium called glands. These tissue architectural elements are maintained with the contribution of morphogen signals. Morphogens are expressed in specific areas of the tissue, and their diffusion generates gradients in the microenvironment. Cells at different positions in the gland sense a specific combination of signals that instruct them to differentiate, proliferate, regenerate, or migrate. Differentiated cells perfo...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3390/ijms23073632

Authors


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Role:
Author
ORCID:
0000-0001-5280-8261
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Oxford Ludwig Institute
Role:
Author
Publisher:
MDPI
Journal:
International Journal of Molecular Sciences More from this journal
Volume:
23
Issue:
7
Article number:
3632
Publication date:
2022-03-26
Acceptance date:
2022-03-23
DOI:
EISSN:
1422-0067
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1248874
Local pid:
pubs:1248874
Deposit date:
2022-03-30

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