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A short history of hemogenic endothelium

Abstract:

Definitive hematopoietic cells are generated de novo during ontogeny from a specialized subset of endothelium, the so-called hemogenic endothelium. In this review we give a brief overview of the identification of hemogenic endothelium, explore its links with the HSC lineage, and summarize recent insights into the nature of hemogenic endothelium and the microenvironmental and intrinsic regulators contributing to its transition into blood. Ultimately, a better understanding of the processes con...

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Publisher copy:
10.1016/j.bcmd.2013.09.005

Authors


De Bruijn, MFTR More by this author
Journal:
Blood Cells, Molecules, and Diseases
Volume:
51
Issue:
4
Pages:
206-212
Publication date:
2013-12-05
DOI:
EISSN:
1096-0961
ISSN:
1079-9796
URN:
uuid:7c97ee35-d15e-4250-932a-1c99df7cc3c6
Source identifiers:
438647
Local pid:
pubs:438647

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